• U.S. Brand Names: PliaglisT;SyneraT
• Pharmacologic Category: Analgesic, Topical;Local Anesthetic

• This medicine is used to numb an area of the skin before a procedure.
• Lidocaine and tetracaine numb the area.
• It warms the skin.

How to take

• This medicine is applied to the skin.
• Your healthcare provider will give this medicine.

Storage

• This medicine will be given to you in a healthcare setting. You will not store it at home.

Avoid

• If you have an allergy to lidocaine, tetracaine, or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

Precautions

• If you have liver disease, talk with healthcare provider.
• The patch may contain conducting metal. Remove patch before MRI.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Do not put coverings (bandages, dressings, make-up) over the area unless told to do so by healthcare provider.
• Use caution on skin where a large area is involved or where there are open wounds.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.

Side Effects

• Skin irritation.

Monitoring

• Change in condition being treated. Is it better, worse, or about the same?

Contact a healthcare provider

• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Difficulty breathing.
• Fast heartbeat.
• Any pain during procedure.
• Severe skin irritation.
• Any rash.
• No improvement in condition or feeling worse.

General Statements

• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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