• U.S. Brand Names: Noxafil®
• Canadian Brand Names: PosanolT
• Pharmacologic Category: Antifungal Agent, Oral

• It is used to stop or treat yeast infections.
• Posaconazole works to harm the yeast and fight an infection.

How to take

• To gain the most benefit, do not miss doses.
• Use as told, even if feeling better.
• Take this drug with food.
• Shake well before use.

Missed Dose

• Take a missed dose as soon as you think about it.
• If it is close to time for the next dose, skip the missed dose and return to your normal time.
• Do not take two doses or extra doses.
• Do not change dose or stop drug. Talk with doctor.

Storage

• Store at room temperature.
• Protect from light.

Warnings

• Unsafe reactions may happen. This drug cannot be taken while you are taking certain other drugs. Check all the drugs you are taking with your doctor.

Avoid

• If you have an allergy to posaconazole or any other part of this drug.
• Tell doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs involved.

Precautions

• Check all drugs you are taking with your doctor. This drug may not mix well with certain other drugs.
• If you have a fast heartbeat, talk with doctor.
• If you have kidney disease, talk with doctor.
• If you have liver disease, talk with doctor.
• If you have low magnesium levels, talk with doctor.
• If you have low potassium levels or if you are taking a water pill, talk with doctor.
• Tell doctor if you cannot take this drug with food.
• Avoid grapefruit and grapefruit juice.
• Avoid alcohol (includes wine, beer, and liquor).
• Tell doctor if you are pregnant or plan on getting pregnant.
• Tell doctor if you are breast-feeding.

Side Effects

• Upset stomach or throwing up. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Loose stools.
• Belly pain.
• Headache.
• High or low blood pressure.
• Swelling.
• Feeling tired or weak.
• Constipation.
• Low potassium level. Signs include feeling tired, weak, numbness, or tingling; muscle cramps; constipation; throwing up; or fast heartbeat.
• Liver damage can rarely happen.

Monitoring

• Change in health problem being treated. Is it better, worse, or about the same?

Contact a healthcare provider

• If you suspect an overdose, call your local poison control center or ER right away.
• Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
• Trouble breathing.
• Very bad swelling.
• Fast heartbeat or passing out.
• Very bad belly pain.
• Very bad loose stools.
• Very upset stomach or throwing up.
• Not able to eat.
• Signs of low potassium.
• Major weight gain.
• Dark urine or yellow skin or eyes.
• Feeling very tired or weak.
• Any rash.
• Health problem is not better or you are feeling worse.

General Statements

• If you have a very bad allergy, wear allergy ID at all times.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep all drugs out of the reach of children and pets.
• Most drugs can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• In Canada return any unused drugs back to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th for more facts about the right way to get rid of unused drugs.
• Keep a list of all your drugs (prescription, natural products, supplements, vitamins, OTC) with you. Give this list to your doctor.
• Call your doctor for health help about side effects. You may also call the FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with doctor before starting any new drug, including OTC, natural products, or vitamins.

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